Dr. Polidoro graduated from Connecticut College with a Bachelor's degree in Zoology in 1990 and from the University of California, Davis with his Doctorate of Veterinary Medicine in 1998. Post graduation, he completed a 1-year internship at California Animal Hospital, Department of Surgery in Los Angeles. Upon completion, he returned to San Francisco and worked in general practice for a year. This was followed by a role as a Senior Scientist at a Bay Area multinational healthcare company, Baxter Healthcare, in the Biosurgery Division. There he worked with a team of scientists to develop innovative biomaterial-based medical devices for use in human and companion animal surgery. He then pursued a 3-year residency in small animal surgery at the Animal Surgical and Emergency Center in Los Angeles where he continued his practice as a small animal surgeon for eleven years. He became a Diplomate of the American College of Veterinary Surgeons - Small Animal (DACVS-SA) in 2013.

In 2017, Dr. Polidoro returned to specialty practice in Northern California and has practiced surgery in the San Francisco Bay Area since. He is a founding member of the medical team at San Francisco Animal Medical Center. As a board-certified surgeon, Dr. Polidoro’s practice focuses on complex, non-routine orthopedic and soft tissue procedures. Outside of work he enjoys local hiking, attending the theater and spending time with his husband, two Standard Poodles (Elphaba and Chino) and his tuxedo cat (Roy).